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CV of Dr. rer. nat. Christian RA Regenbrecht

Personal details

NameDr. Christian RA Regenbrecht
D-O-B28-Apr-1975
NationalityGerman
Present addressMax Planck Institute for Molecular Genetics
Ihnestr. 73
14195 Berlin, Germany
fon: +49 30-8413-1490
fax: +49 30-8413-1406
email: mail[at]christian-regenbrecht.de


Education

1994Abitur („A levels“)
1995-1996Studies of medicine at University of Rostock
1996Studies of biology at University of Mainz
1997-2000 Studies of biology at the Rheinische Friedrich-Wilhelms University of Bonn
2001-2002Diploma thesis „The ectodomain of the Alzheimer amyloid precursor protein as a morphogenic factor for wing development in Drosophila melanogaster“ at the Institute of cell biology, University of Bonn (Grade: "sehr gut")
2002-2005PhD thesis „Epigenetic regulation in human gliomas“, Institute for Neuropathology, University of Bonn Medical Ctr. and the German Cancer Research Center (DKFZ), Heidelberg. (Grade: "magna cum laude")

 

Additional training

since 2002 Approval as supervisor for animal experiments according to FELASA reglementaries
from 09/2008Approval and Appointment as Biosafety Officer


Professional experience

2005-2007Post doctoral position in Dr. Lange's group (Dept. Prof. Lehrach) at the MPI for molecular genetics
2007-2008Project on "Cancer Stem Cells" together with Dr. James Adjaye (Dept. Prof. Lehrach) at the MPI for Molecular Genetics
since 01/09Group leader "Cancer Stem Cells & personalized medicine" at the MPI for Molecular Genetics


Memberships

European Association for Cancer Research (EACR): website

Deutsche Gesellschaft für Zellbiologie (DGZ): website

New York Academy of Science (NYAS); website

 


Grant applications

2005- 2007 Fritz-Thyssen-Stiftung: "Hsp90 in cancerogenesis", together with PD Dr. B. Lange
2007-2008 Gisela-Stadelmann-Stiftung "Cancer stem cells", together with Prof. Dr. R. Tikkanen
2008-2009Berliner Krebsgesellschaft, together with Dr. J. Adjaye
2009-2011Wilhelm Sander-Stiftung, together with Dr. J. Adjaye


Original papers

Regenbrecht CRA, Lehrach H, Kindler-Röhrborn A, Kölsch B, A rodent model for nephroblastoma [in preparation]

Susanne Frank, Susanne A. Kuhn, Michael Brodhun, Ulrike Mueller, Bernd Romeike, Hartwig Kosmehl, Christian RA Regenbrecht, Christian Ewald, Rupert Reichart, Rolf Kalff, Metastatic glioblastoma cells use common pathways via blood and lymphatic vessels. Neurologia i Neurochirurgia Polska 2009; 43, 2:

Brink TC, Regenbrecht C, Demetrius L, Lehrach H, Adjaye J. Activation of the immune response is a key feature of aging in mice. Biogerontology. 2009 Mar 3. [Epub ahead of print]

Regenbrecht C RA, Welte Y, Jödicke A, Hugel R, Walden P, Jung M, Lehrach H, Adjaye J, Molecular characterization of signaling pathways in cancer stem cells, ecancermedicalscience

Regenbrecht CRA, Welte Y, Hugel R, Trefzer U, Losch FO, Adjaye J & Walden P, Cancer Stem Cells in Melanom, ecancermedicalscience [link]

Regenbrecht CRA, Jung M, Lehrach H, Adjaye J, The molecular basis of phytoestrogene Genistein induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines, BMC Medical Genomics, 2008 [link]
Regenbrecht CRA, Lehrach H, Adjaye J, Stemming cancer: Functional genomics of cancer stem cells in solid tumors, Stem Cell Rev 2008 [link]
Regenbrecht CRA, Felsberg J, Pietsch T, Reifenberger G, Huang T, Wiestler OD, Waha A, Analysis of candidate gene methylation on glioma microarrays, Acta Neuropath, 108 (4), 350-51, 2004 [link]


Contributions to scientific meetings & invited lectures

 

Poster presentations

Genomics of Cancer Stem Cells in human gliomas, XX. International Congress of Genetics (ICG) , 2008, Berlin, Germany
Enrichment and Isolation of CD133+ Cells from solid human tumors, 3rd Mildred-Scheel Cancer Conference, 2008, Bonn, Germany
Hsp90 in cancer, Annual meeting of the NGFN2, 2005, Bonn, Germany
Analysis of candidate gene methylation on glioma microarrays, German Society for Neuropathology and neuroanatomy, 2004, Cologne, Germany
Function of the ectodomain of Alzheimer amyloid precursor protein in morphogenesis of epithelia, Annual meeting of the American Society for Cell Biology, December 8-12, 2001, Washington DC
Function of the ectodomain of Alzheimer amyloid precursor protein in morphogenesis of epithelia, Annual meeting of the American Society for Cell Biology, December 8-12, 2001, Washington DC

 

Invited lectures

Stammzellen als Ursache von Krebs, 2008, Urania, Berlin, Germany
Cancer Stem Cells in Human Gliomas, 2008, Clinic for Neurosurgery, Vivantes Klinik Neukölln
Enrichment and Isolation of CD133+ Cells from Solid Human Tumors, Charité Comprehensive Cancer Center Workshop-meeting, 2008, Berlin, Germany
Krebs-Stammzellen? Stammzellen-Krebs? Bionnale Speed Lecture Award, 2008, Berlin, Germany
Relevance of CD133+ Cells in Diagnostics and Therapy, Institute for children's oncology, Charité Berlin, 2008, Berlin, Germany
Enrichment and Isolation of CD133+ Cells from solid human tumors Institute for Dermatology, Charité Berlin, 2008, Berlin, Germany
A rodent model for Nephroblastoma, Institute for children's oncology, Charité Berlin, 2007, Berlin, Germany
Hsp90 interactions in cancer, Cancer Net of the NGFN2, 2005 Germany
Array based methylation analysis in gliomas, Annual meeting of the German Society for Neuropathology and Neuroanatomy, Cologne, Germany
Methylation analysis in human gliomas, NCI, 2005, Amsterdam, The Netherlands
Finding methylation - an overview, Insitute for Biochemistry II, University Frankfurt/ Main, Germany
Methylation analysis in human gliomas, Max-Planck-Institute for Molecular Genetics, Berlin, Germany
DMH and MTA - an approach to high-throughput methylation analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany
Implanting telemetric devices, DSI workshop, 2002, Germany